Computational analysis of ChIP-seq data.
نویسنده
چکیده
Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a new technology to map protein-DNA interactions in a genome. The genome-wide transcription factor binding site and chromatin modification data produced by ChIP-seq provide invaluable information for studying gene regulation. This chapter reviews basic characteristics of ChIP-seq data and introduces a computational procedure to identify protein-DNA interactions from ChIP-seq experiments.
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عنوان ژورنال:
- Methods in molecular biology
دوره 674 شماره
صفحات -
تاریخ انتشار 2010